Levels of Care

The Detox Timeline: What to Expect Day by Day

Medically reviewed by Reform Recovery's clinical team · Reform Recovery Center, Burbank, CA

Published Feb 14, 2026 · Updated Jul 8, 2026

Detox timelines vary by substance and person, but knowing the general arc helps take away the fear. Here's what to expect — always under medical supervision.

Alcohol withdrawal (general)

• 6–12 hours: anxiety, shakiness, sweating begin.
• 24–72 hours: symptoms peak; this window carries the highest medical risk, which is why supervision matters.
• 5–7 days: acute symptoms ease and stabilize.

Opioid withdrawal (general)

• 8–24 hours: early symptoms — restlessness, aches, cravings.
• Days 1–3: symptoms peak; flu-like and intense but rarely life-threatening with support.
• Days 4–7: physical symptoms subside.

An important caution

Alcohol and benzodiazepine withdrawal can be medically dangerous — never attempt them alone. Medical detox provides monitoring and medication to keep you safe and far more comfortable.

After the acute phase

Some symptoms (sleep, mood, cravings) can linger for weeks as post-acute withdrawal. That's normal and manageable — and exactly why continuing into treatment matters.

This article is educational and is not medical advice or a substitute for professional care. If you or someone you love is in crisis, call the SAMHSA National Helpline (free & confidential, 24/7): 1-800-662-4357.